<!-- Amiloxate (IMC): is it reef safe? | Reef Label -->
Source: https://reeflabel.com/ingredients/amiloxate/

Chemical (organic) UV filter · Reef research: Limited data

# Amiloxate (IMC)

A cinnamate UVB filter used outside the US.

Banned in

-   Palau

Also excluded where only mineral sunscreen is allowed

-   Maui County
-   Hawaiʻi County

Not approved in the US, so US sunscreens do not contain it.

## Where it’s restricted

Named in the law or guidance

| Location | Status | Since |
| --- | --- | --- |
| [Palau](https://reeflabel.com/locations/palau/) [law text ↗](https://www.palaugov.pw/wp-content/uploads/2018/10/RPPL-No.-10-30-re.-The-Responsible-Tourism-Education-Act-of-2018.pdf) | In force | January 1, 2020 |

### Also not allowed under mineral-only rules

Amiloxate (IMC) isn’t named in these laws, but they allow only mineral (zinc oxide or titanium dioxide) sunscreens, so a product containing it is excluded anyway.

-   [Maui County (Maui, Molokaʻi, Lānaʻi)](https://reeflabel.com/locations/maui-county/) (in force since October 1, 2022)
-   [Hawaiʻi County (Big Island)](https://reeflabel.com/locations/hawaii-county/) (in force since December 1, 2022)

## What the reef research says

Mitchelmore et al. (2019) found amiloxate below the limit of detection in sediment at sites near coral reefs, as tabulated in a 2021 critical review of UV filters and corals. A 2025 study of Polish freshwater recreational lakes found it among the main contributors to moderate cumulative risk, with localized high-risk values at Kryspinów, but those sites were freshwater, not reef. In a controlled off-site experiment with surface water in natural light, O’Malley et al. (2021) estimated a 6.6 hour half-life for amiloxate. No coral toxicity study of amiloxate was found in the sources read for this entry, so its effect on corals is unknown.

Sources (4)

-   [O'Malley et al. 2021, Sci Total Environ 754:142373 (PubMed record)](https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=33254898&rettype=abstract&retmode=text)
-   [Stolecka et al. 2025, Water Res 279:123423 (PubMed record)](https://eutils.ncbi.nlm.nih.gov/entrez/eutils/efetch.fcgi?db=pubmed&id=40056475&rettype=abstract&retmode=text)
-   [Mitchelmore et al. 2021, Environ Toxicol Chem: critical review of organic UV filter exposure, hazard and risk to corals (PMC)](https://pmc.ncbi.nlm.nih.gov/articles/PMC8048829/)
-   [FDA: Questions and answers on FDA regulatory actions on over-the-counter sunscreen](https://www.fda.gov/drugs/understanding-over-counter-medicines/questions-and-answers-fdas-regulatory-actions-over-counter-sunscreen)

## What to look for instead

-   [Zinc Oxide](https://reeflabel.com/ingredients/zinc-oxide/)
-   [Titanium Dioxide](https://reeflabel.com/ingredients/titanium-dioxide/)

**Related ingredients:** [Octinoxate](https://reeflabel.com/ingredients/octinoxate/), [Octocrylene](https://reeflabel.com/ingredients/octocrylene/)

Last reviewed October 14, 2026.

### Label names we match

-   amiloxate
-   isoamyl p-methoxycinnamate
-   isoamyl methoxycinnamate

### Regulatory status

**Wikidata:** [Q17012246](https://www.wikidata.org/wiki/Q17012246)

**US FDA:** Not approved in the US.

**EU:** Approved, max 10%.

**Protects against:** UVB.
